Phenylthiosemicarbazide as an Analytical Reagent. III

Spectrophotometric Determination of Drugs Using Iodine As Analytical Reagent

Six drugs viz., Astemizole, Cisapride, Domperidone, Pantoprazole, Rabeprazole and Trazadone were tested for the formation of charge transfer complexes with Iodine. Each of these drugs turned the violet coloured i.e iodine , in CH2Cl2, to brown and exhibited a new band at 366nm in addition to the original band of iodine at 510nm due to anion of the reagent whose intensity increased with increase...

Phenylbiguanide-p-Sulfonic Acid as an Analytical Reagent for the Colorimetric Determination of Nickel

[Glucose oxidase as an analytic reagent].

Glucose oxidase (EC 1.1.3.4) is the most widely employed enzyme as analytical reagent. This is the result of (1) its utility in the determination of glucose, an analyte of wide analytical interest, and (2) its relatively low cost and good stability that make the glucose/glucose oxidase system a very convenient model for method development (particularly in the area of biosensors). This review di...

Spectrophotometric determination of Drugs & Pharmaceuticals Using Cerium(IV) as oxidant and Amaranth dye as analytical reagent

Simple, sensitive and accurate methods for determination of four drugs viz., Ciprofloxacin, Pantoprazole Sodium Sesquihydrate, Atrovastatin Calcium and Rosuvastine Calcium have been developed. The methods depend upon the oxidation of the drug by a known excess Ceric Ammonium Sulphate in sulphuric acid medium and subsequent determination of unreacted Ce (IV) using Amaranth dye. The methods have ...

Phenylsilane as an effective desulfinylation reagent

The reduction using phenylsilane in a KOH-catalyzed system was applied successfully to the conversion of sulfinyl-substituted cyclopropylcarboxylates into the corresponding alcohols. The presence of sulfinyl substituents in the α-position to the carboxylate group caused a desulfinylation product formation with full regio- and stereoselectivity, instead of a carbonyl group reduction. Investigati...